PRESEASON
| DATE | OPPONENT | TIME (CST) | NETWORK |
| Thu, Aug 11 | New York Giants | 6:00 PM | Patriots Preseason TV Network |
| Fri, Aug 19 | Carolina Panthers | 6:00 PM | Patriots Preseason TV Network |
| Fri, Aug 26 | at Las Vegas Raiders | 7:15 PM | Patriots Preseason TV Network |
REGULAR SEASON
| WEEK | DATE | OPPONENT | TIME (CST) | NETWORK |
| 1 | Sun, Sep 11 | at Miami Dolphins | 12:00 PM | CBS |
| 2 | Sun, Sep 18 | at Pittsburgh Steelers | 12:00 PM | CBS |
| 3 | Sun, Sep 25 | Baltimore Ravens | 12:00 PM | FOX |
| 4 | Sun, Oct 2 | at Green Bay Packers | 3:25 PM | CBS |
| 5 | Sun, Oct 9 | Detroit Lions | 12:00 PM | FOX |
| 6 | Sun, Oct 16 | at Cleveland Browns | 12:00 PM | CBS |
| 7 | Sun, Oct 24 | Chicago Bears | 7:15 PM | ESPN |
| 8 | Sun, Oct 30 | at New York Jets | 12:00 PM | CBS |
| 9 | Sun, Nov 6 | Indianapolis Colts | 12:00 PM | CBS |
| 10 | BYE WEEK | – | – | – |
| 11 | Sun, Nov 20 | New York Jets | 12:00 PM | CBS |
| 12 | Thu, Nov 24 | at Minnesota Vikings | 7:20 PM | NBC |
| 13 | Thu, Dec 1 | Buffalo Bills | 7:15 PM | PRIME VIDEO |
| 14 | Mon, Dec 12 | at Arizona Cardinals | 7:15 PM | ESPN |
| 15 | Sun, Dec 18 | at Las Vegas Raiders | 7:20 PM | NBC |
| 16 | Sat, Dec 24 | Cincinnati Bengals | 12:00 PM | CBS |
| 17 | Sun, Jan 1 | Miami Dolphins | 12:00 PM | CBS |
| 18 | Sat/Sun, Jan 7/8 | at Buffalo Bills | TBD | TBD |
